Authors
Garcia-Rojas IJ; Omidakhsh N; Arah OA; Krause N
Source
Front Public Health 2021 Jun; 9:683655
Abstract
Background: Cardiovascular disease is becoming increasingly prevalent in low and middle-income countries (LMIC), and high blood pressure (BP) is one of the main risk factors. The efficacy and sustainability of worksite health promotion (WHP) programs for BP reduction in LMIC have yet to be determined. Methods: This non-randomized company-based trial evaluated 6- and 12-months effects of a WHP intervention on BP among 2,002 participating workers from seven Mexican companies. Intervention and control groups were assigned at the company level. The intervention included nutrition counseling, physical exercise, and stress management components. Mixed models assessed differences in BP change between intervention and control companies in intent-to-treat (ITT), per-protocol (PerP), and as-treated (AsTr) analyses, and also within-group changes stratified by company, intervention component, and baseline cardiovascular risk factor levels. All analyses were adjusted for potential confounders. We accounted for missing data and loss to follow-up using inverse probability of censoring weighting. Results: ITT analyses revealed mean BP change differences of -1.1 mmHg at 12 months (95% CI: -2.9; 0.6) in intervention companies relative to control companies. PerP and AsTr analyses confirmed this finding. Within-group analyses showed consistent BP reductions at both 6 and 12 months. Substantial differences in BP changes ranging from diastolic -6.1 mmHg, (95% CI: -11.2; -1.2) to systolic -13.0 mmHg (95% CI: -16.0; -10.1) were found among individuals with diabetes at baseline in intervention companies relative to control companies. Conclusion: After 1 year, WHP was associated with modest but uncertain BP reductions. Substantial reductions were mainly observed among diabetic workers.
Keywords
Blood pressure; Minority health; Immigrant workers; Cardiovascular disease; Health promotion; Intervention; Nutrition; Physical exercise; Stress; Managed care;
Author Keywords: cardiovascular risk factors; intervention study; workplace; health promotion; blood pressure; diabetes mellitus; Mexico; multilevel analysis
Contact
Niklas Krause, Fielding School of Public Health, Department of Environmental Health Sciences, University of California, Los Angeles, Los Angeles, CA
Document Type
Journal Article
Email Address
niklaskrause@ucla.edu
Identifying No.
Grant-Number-T42-OH-008412
Source Name
Frontiers in Public Health
Performing Organization
University of California Los Angeles
