Each year in the U.S., pneumococcal disease accounts for over 100,000 hospitalizations for pneumonia. As many as 35% of pneumococcal isolates may have intermediate or high-level resistance to penicillin; many of these isolates are also resistant to other antimicrobial drugs, thus complicating the management of pneumococcal infection. Such emerging antimicrobial resistance further emphasizes the need for preventing pneumococcal infection.
Source: Fact Sheet on Streptococcus pneumoniae Disease. Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, CDC. The Fact Sheet may be accessed at: http://www.cdc.gov/ncidod/dbmd/diseaseinfo/streppneum_t.htm.