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Epi Facts   Approximately how many hospitalizations for pneumonia can be attributed to pneumococcal disease in the U.S. each year? Pneumococcal disease causes 25,000 hospitalizations each year. Pneumococcal disease causes 50,000 hospitalizations each year. Pneumococcal disease causes 100,000 hospitalizations each year. Pneumococcal disease causes 200,000 hospitalizations each year. < back to questions