Increasing Adult Vaccination Rates What Works
 
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Over 80% of acute hepatitis B virus (HBV) infections occur among adults; 25% of all persons with HBV infection have no known cause.

Annually 4,000-5,000 die from HBV-induced chronic liver disease and primary hepatocellular carcinoma.

Prevalence of Hepatitis B in Various Population Groups

Population Group Prevalence of Serologic Markers of HBV Infection
  HBsAg(%) All Markers (%)
HIGH RISK    
Immigrants/refugees from areas of high HBV endemicity. 13 70-85
Clients in institutions for the developmentally disabled. 10-20 35-80
Users of illicit parenteral drugs. 7 60-80
Homosexually active men. 6 35-80
Patients of hemodialysis units. 3-10 20-80
Household contacts of HBV carriers 3-6 30-60
INTERMEDIATE RISK    
Prisoner (male). 1-8 10-80
Health care workers-frequent blood contact. 1-2 15-30
Staff of institutions for the mentally retarded. 1 10-25
Heterosexuals with multiple partners. 0.5 5-20
LOW RISK    
Health care workers-no or infrequent blood contact. 0.3 3-10
Healthy adults (first time volunteer blood donor's). 0.3 3-5

Source: : Epidemiology and Prevention of Vaccine-Preventable Diseases (the Pink Book), Centers for Disease Control and Prevention, 10th Edition, 2007, p. 218.   

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