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 1 The validation of work-related self-reported asthma exacerbation
Authors Bolen-AR; Henneberger-PK; Liang-X; Sama-SR; Preusse-PA; Rosiello-R; Milton-DK 
Source Occup Environ Med 2007 May; 64(5):343-348 
Link http://dx.doi.org/10.1136/oem.2006.028662 
NIOSHTIC No. 20031665 
AbstractObjective: To determine the validity of work-related self-reported exacerbation of asthma using the findings from serial peak expiratory flow (PEF) measurements as the standard. Methods: Adults with asthma treated in a health maintenance organisation were asked to conduct serial spirometry testing at home and at work for 3 weeks. Self-reported respiratory symptoms and medication use were recorded in two ways: a daily log completed concurrently with the serial PEF testing and a telephone questionnaire administered after the PEF testing. Three researchers evaluated the serial PEF records and judged whether a work relationship was evident. Results: 95 of 382 (25%) working adults with asthma provided adequate serial PEF data, and 13 of 95 (14%) were judged to have workplace exacerbation of asthma (WEA) based on these data. Self-reported concurrent medication use was the most valid single operational definition, with a sensitivity of 62% and a specificity of 65%. Conclusions: a work-related pattern of self-reported asthma symptoms or medication use was usually not corroborated by serial PEF testing and failed to identify many people who had evidence of WEA based on the serial PEF measurements. 
KeywordsWorkers; Worker-health; Bronchial-asthma; Occupational-health; Occupational-diseases; Diseases; Spirometry; Respiratory-system-disorders 
ContactPK Henneberger, National Institute for Occupational Safety and Health/CDC, M/S H2800, 1095 Willowdale Road, Morgantown, WV 265 
CODENOEMEEM 
Publication Date20070501 
Document TypeJournal Article 
Email Addresspkh0@cdc.gov 
Fiscal Year2007 
NTIS Accession No. 
NTIS Price 
Issue of Publication5 
ISSN1351-0711 
NIOSH DivisionDRDS 
Source NameOccupational and Environmental Medicine 
StateWV; MA 
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