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Mortality of workers employed in shoe manufacturing: an update.

Authors

Lehman-EJ; Hein-MJ

Source

Am J Ind Med 2006 Jul; 49(7):535-546

Link

http://dx.doi.org/10.1002/ajim.20322 

NIOSHTIC No.

20030502 

Abstract

In the late 1970s, the National Institute for Occupational Safety and Health identified two shoe manufacturing facilities where workers experienced relatively "pure" exposures to toluene. A mortality study was conducted through December 31, 1982. An original study did not detect elevated leukemia mortality but did detect increased lung cancer mortality. The present study is an update of the mortality of the original cohort. The study cohort consisted of workers employed 1 month or more between 1940 and 1979 at two Ohio shoe manufacturing plants. Vital status was ascertained through December 31, 1999. Seven thousand eight hundred twenty eight workers, contributing 300,777 person years, were available for analysis. An excess of lung cancer deaths persisted with additional years of follow-up (SMR = 1.36, 95% confidence interval (CI) = 1.19-1.54). Trend tests did not indicate a positive trend between lung cancer risk and duration of employment. Mortality from leukemia was not significantly elevated in the updated analysis. Results indicate a possible association between lung cancer mortality and exposure to chronic, low-levels of organic solvents. Although the strength of this conclusion was weakened by the lack of increasing lung cancer risk in relation to duration of employment, other studies have supported this association.

Keywords

Shoe-manufacturing; Workers; Mortality-data; Mortality-rates; Worker-health; Employees; Employee-health; Toluenes; Solvents; Lung-cancer; Cancer; Xylenes; Occupational-exposure; Occupational-health; Pulmonary-system-disorders; Employee-exposure; Risk-factors; Risk-analysis; Chronic-exposure; Organic-solvents

Contact

Everett J. Lehman, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, The National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-13, Cincinnati, OH 45226

CODEN

AJIMD8

CAS No.

1330-20-7; 108-88-3

Publication Date

20060701

Document Type

Journal Article

Email Address

ELehman@cdc.gov

Fiscal Year

2006

NTIS Accession No.

NTIS Price

Issue of Publication

7

ISSN

0271-3586

NIOSH Division

DSHEFS

Source Name

American Journal of Industrial Medicine

State

OH