Problem: In today’s economic environment, enterprises may not be able to fund every new project aimed at promoting health and safety in the workplace. Company level economic evaluation of interventions can provide guidance in sound business decision-making. The Economic Evaluation of Occupational Health and Safety Interventions at the Company Level Meeting brought together members of the global occupational safety and health community interested in encouraging the use of economic knowledge and tools to evaluate economic gains from occupational health and safety interventions. Discussion: Discussions of the six models presented explored similarities, reliability, and potential use by corporate enterprises, small and medium enterprises, developing and transitioning nations, and economic theorists. Each group provided specific projects that could be pursued to advance knowledge in the area of economic evaluation at the company level. Conclusion: This conference established pathway to incorporate economic evaluation of health and safety interventions or programs at the workplace.