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Clinical and occupational outcomes in health care workers with natural rubber latex allergy.

Authors

Bernstein-D; Karnani-R; Biagini-R; Berstein-C; Murphy-K; Berendts-B; Bernstein-J; Bernstein-I

Source

Ann Allergy, Asthma, & Immun 2003 Feb; 90(2):209-213

Link

http://dx.doi.org/10.1016/S1081-1206(10)62143-6 

NIOSHTIC No.

20022369 

Abstract

There is limited information pertaining to clinical outcomes and economic consequences of natural rubber latex (NRL) allergy in health care workers (HCWs). To evaluate retrospectively health and economic outcomes in HCWs identified with NRL allergy and percutaneous reactivity to NRL. Sixty-seven HCWs with NRL allergy, confirmed by percutaneous reactivity to non-ammoniated latex (NAL) extract, were administered a detailed questionnaire to evaluate clinical and economic outcomes of active work and environmental interventions subsequent to recognition of work-related symptoms associated with NRL gloves. Diagnoses based on predetermined case definitions associated with direct or indirect exposure to NRL gloves included contact urticaria in 67 (100%); work-related rhinitis in 23; work-related asthma symptoms in 25; and work-related anaphylaxis in 4 workers. Work related symptoms reportedly resolved in 44 of 49 (90%) of NAL skin test-positive workers who had reported skin, respiratory, and/or systematic symptoms and remained in their current work area and who switched to non-NRL gloves. Four of 24 (17%) workers with work-related asthma symptoms were compelled to change employment to NRL-safe workplaces, resulting in a mean 24% reduction in annual income. Clinical outcomes in this group of HCWs with NRL allergy were favorable after institution of interventions but incurred deleterious consequences in a minority of workers.

Keywords

Health-care-personnel; Allergic-reactions; Allergies; Occupational-health; Occupational-exposure; Gloves; Respiratory-system-disorders; Respiratory-irritants; Pulmonary-system-disorders

Contact

University of Cincinnati College of Medicine, Division of Immunology, Department of Internal Medicine, Cincinnati, Ohio 45267-0563, USA

CODEN

ALAIF6

Publication Date

20030201

Document Type

Journal Article

Email Address

bernstdd@email.uc.edu

Fiscal Year

2003

NTIS Accession No.

NTIS Price

Issue of Publication

2

ISSN

1081-1206

NIOSH Division

HELD; DART

Source Name

Annals of Allergy, Asthma, and Immunology

State

OH