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Respiratory morbidity in office workers in a water-damaged building |
| Authors |
Cox-Ganser-JM; White-SK; Jones-R; Hilsbos-K; Storey-E; Enright-PL; Rao-CY; Kreiss-K |
| Source |
Environ Health Perspect 2005 Apr; 113(4):485-490 |
| Link |
http://www.ehponline.org/docs/2005/7559/abstract.html |
| NIOSHTIC No. |
20026466 |
| Abstract | We conducted a study on building-related respiratory disease and associated social impact in an office building with water incursions in the northeastern United States. An initial questionnaire had 67% participation (888/1,327). Compared with the U.S. adult population, prevalence ratios were 2.2-2.5 for wheezing, lifetime asthma, and current asthma, 3.3 for adult-onset asthma, and 3.4 for symptoms improving away from work (p < 0.05). Two-thirds (66/103) of the adult-onset asthma arose after occupancy, with an incidence rate of 1.9/1,000 person-years before building occupancy and 14.5/1,000 person-years after building occupancy. We conducted a second survey on 140 respiratory cases, 63 subjects with fewer symptoms, and 44 comparison subjects. Health-related quality of life decreased with increasing severity of respiratory symptoms and in those with work-related symptoms. Symptom status was not associated with job satisfaction or how often jobs required hard work. Respiratory health problems accounted for one-third of sick leave, and respiratory cases with work-related symptoms had more respiratory sick days than those without work-related symptoms (9.4 vs. 2.4 days/year; p < 0.01). Abnormal lung function and/or breathing medication use was found in 67% of respiratory cases, in 38% of participants with fewer symptoms, and in 11% of the comparison group (p < 0.01), with similar results in never-smokers. Postoccupancy-onset asthma was associated with less atopy than preoccupancy-onset asthma. Occupancy of the water-damaged building was associated with onset and exacerbation of respiratory conditions, confirmed by objective medical tests. The morbidity and lost work time burdened both employees and employers. | | Keywords | Respiratory-system-disorders; Hypersensitivity; Environmental-exposure; Environmental-hazards; Lung-function; Morbidity-rates; Office-workers; Pulmonary-system-disorders; Microorganisms |
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