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Course Detail

Activity Title

Guidelines for the Prevention and Treatment of Opportunistic Infections Among HIV-Exposed and HIV-Infected Children : Recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics
CE Original Date: 09/04/2009
CE Renewal Date:
CE Expiration Date: 09/04/2012


This goal of this report is to provide evidence-based guidelines for treatment of opportunistic pathogens that are common in human immunodeficiency virus (HIV)-exposed and HIV-infected children in the United States. This report provides guidelines for clinicians and health-care professionals regarding treatment of opportunistic pathogens in children. Upon completion of this activity, the reader should be able to


  1. Describe the differences between HIVinfected children in the clinical presentation and laboratory diagnosis of HIV-associated opportunistic infections;
  2. Describe recommended treatment of HIV-related opportunistic infections in HIV-infected children;
  3. Describe recommendations for screening for M. tuberculosis infection in HIV-infected children;
  4. Describe treatment of suspected congenital syphilis in HIV-exposed infants and
  5. Describe recommendations for secondary chemoprophylaxis of HIV-infected children following infection with HIV-associated opportunistic pathogens.

Intended Audience


Presenters/Content Experts

Michael Brady, MD, Nationwide Children’s Hospital

Kenneth L. Dominguez, MD, MPH, Medical Epidemiologist, Maternal Child Transmission, Clinical Epidemiologic Studies Team, Epidemiology Branch, Division of HIV/AIDS Prevention, NCHHSTP/CDC

Edward Handelsman, MD, Chief, Division of AIDS National Institute of Allergy & Infectious Diseases, NIH

Peter Havens, MD, Infectious Diseases Consultant, Heart Transplantation Program, Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Lynne M. Mofenson, MD, Chief, Pediatric, Adolescent and Maternal AIDS Branch, National Institute of Child Health and Human Development

Steven Nesheim, MD, Team Leader, Mother to Child Transmission Epidemiology Branch, NCHHSTP/CDC

Jennifer Read, MD, MS, MPH, DTM & H, Pediatric, Adolescent, and Maternal AIDS (PAMA) Branch, NIH Leslie Serchuck, MD, Medical Officer in the Pediatric, Adolescent and Maternal AIDS Branch, NIH, National Institute of Child Health and Human Development Russell Van Dyke, MD, Professor of Clinical Pediatrics, Tulane University School of Medicine


  • Continuing Nursing Education (CNE) Credit

  • The CDC is accredited as a provider of Continuing Nursing Education by the American Nurses Credentialing Center's Commission on Accreditation.
    This activity provides 3.25 contact hours.

  • Continuing Medical Education (CME) credit

  • The CDC is accredited by the Accreditation Council for Continuing Medical Education (ACCME®) to provide continuing medical education for physicians.

    The CDC designates this educational activity for a maximum of 3.25 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

  • IACET Continuing Education Unit (CEU) Credit

  • The CDC has been approved as an Authorized Provider by the International Association for Continuing Education and Training (IACET), 1760 Old Meadow Road, Suite 500, McLean, VA. The CDC is authorized by IACET to offer 0.3 ANSI/IACET CEU's for this program.
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